VIP
| SMILES | None |
| InChIKey | VBUWHHLIZKOSMS-UHFFFAOYSA-N |
| Sequence | HSDAVFTDNYTRLRKQMAVKKYLNSILN |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | Yes |
Sankey plot
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Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAC1 | PACR | Human | VIP and PACAP | B1 | pKi | 6.900000000000001 | 6.9 | 6.9 | Guide to Pharmacology |
| PAC1 | PACR | Rat | VIP and PACAP | B1 | pKi | 5.65 | 5.65 | 5.65 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pKi | 9.200000000000001 | 9.2 | 9.2 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pKi | 8.433333333333334 | 8.43 | 8.43 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAC1 | PACR | Human | VIP and PACAP | B1 | pEC50 | 7.0 | 7.0 | 7.0 | Guide to Pharmacology |
| PAC1 | PACR | Human | VIP and PACAP | B1 | pIC50 | 6.0 | 6.0 | 6.0 | Guide to Pharmacology |
| PAC1 | PACR | Rat | VIP and PACAP | B1 | pEC50 | 7.1 | 7.1 | 7.1 | Guide to Pharmacology |
| PAC1 | PACR | Rat | VIP and PACAP | B1 | pIC50 | 5.7 | 5.7 | 5.7 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pEC50 | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Human | VIP and PACAP | B1 | pIC50 | 8.68 | 8.68 | 8.68 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pIC50 | 8.2 | 8.2 | 8.2 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pEC50 | 8.333333333333334 | 8.33 | 8.33 | Guide to Pharmacology |
| VPAC1 | VIPR1 | Rat | VIP and PACAP | B1 | pIC50 | 8.799999999999999 | 8.8 | 8.8 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Rat | VIP and PACAP | B1 | pIC50 | 8.266666666666667 | 8.27 | 8.27 | Guide to Pharmacology |
| secretin | SCTR | Rat | Glucagon | B1 | pIC50 | 6.2 | 6.2 | 6.2 | Guide to Pharmacology |
| VPAC2 | VIPR2 | Human | VIP and PACAP | B1 | pEC50 | 9.72 | 9.72 | 9.72 | ChEMBL |
| secretin | SCTR | Human | Glucagon | B1 | pIC50 | 5.4 | 5.4 | 5.4 | Guide to Pharmacology |