CHEMBL293923


SMILES COc1ccccc1N1CCN(CCc2ccc3c(c2)sc(=O)n3C)CC1
InChIKey RTHIBOYVHBRSHH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 383.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Bovine 5-Hydroxytryptamine A pIC50 6.3 6.3 6.3 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pIC50 8.0 8.0 8.0 ChEMBL
D2 DRD2 Bovine Dopamine A pIC50 7.4 7.4 7.4 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.52 6.52 6.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.4 5.4 5.4 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.7 8.7 8.7 ChEMBL