VU0404251


SMILES Fc1cccc(c1)COc1ccc(cn1)C(=O)N[C@@H](C(C)(C)C)C
InChIKey VOYBJCDMLJODRK-CYBMUJFWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 330.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 7.15 7.15 7.15 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 8.14 8.14 8.14 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pEC50 7.16 7.16 7.16 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 8.14 8.14 8.14 ChEMBL