VU0467154
| SMILES | Cc1c(nnc2c1c(c(s2)C(=O)NCc1ccc(cc1)S(=O)(=O)C(F)(F)F)N)C |
| InChIKey | UDSFKIFLJPECRN-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 444.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
| Structure pdb | 7TRQ |
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pEC50 | 6.2 | 6.2 | 6.2 | Guide to Pharmacology |
| M4 | ACM4 | Rat | Acetylcholine (muscarinic) | A | pEC50 | 7.75 | 7.75 | 7.75 | Guide to Pharmacology |
| M4 | ACM4 | Rat | Acetylcholine (muscarinic) | A | pEC50 | 6.65 | 7.38 | 7.75 | ChEMBL |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pEC50 | 6.2 | 6.48 | 7.04 | ChEMBL |