CHEMBL298612


SMILES Cn1cc(C(=O)C(=O)N[C@@H]2CN3CCC2CC3)c2ccccc21
InChIKey ZNAPADWWBWFMCQ-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 4.8 4.8 4.8 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 4.6 4.6 4.6 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 4.5 4.5 4.5 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 4.6 4.6 4.6 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 4.5 4.5 4.5 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 4.9 4.9 4.9 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 4.6 4.6 4.6 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.6 4.6 4.6 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 4.3 4.3 4.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database