WAY-181187


SMILES NCCc1cn(c2c1cccc2)S(=O)(=O)c1c(Cl)nc2n1ccs2
InChIKey RYBOXBBYCVOYNO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 380.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.66 8.69 8.7 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.34 6.34 6.34 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 8.19 8.19 8.19 ChEMBL