CHEMBL301078


SMILES COc1ccccc1N1CCN(CCNc2ccc3c4c(=O)n(C)nc(Cl)c4cn3n2)CC1
InChIKey STIKULJYVCUQJQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.82 7.82 7.82 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.52 8.52 8.52 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.96 8.96 8.96 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.79 7.79 7.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database