YM298198


SMILES CN(C(=O)c1sc2n(c1C)c1c(n2)ccc(c1)N)C1CCCCC1
InChIKey KCBXOMYXOBVLED-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 342.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations mGlu1

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKd 7.49 7.49 7.49 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pIC50 7.8 7.8 7.8 Guide to Pharmacology
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 6.92 6.92 6.92 Guide to Pharmacology