YM 471


SMILES CN(C1CCN(CC1)C(=O)/C=C\1/c2ccccc2N(CCC1(F)F)C(=O)c1ccc(cc1)NC(=O)c1ccccc1c1ccccc1)C
InChIKey ICRPTZMWRJGNQI-CLIDGEQKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 648.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 9.2 9.2 9.2 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 4.8 4.8 4.8 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 8.9 8.9 8.9 Guide to Pharmacology
V1A V1AR Rat Vasopressin and oxytocin A pKi 9.21 9.51 9.8 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 9.21 9.21 9.21 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 8.92 8.92 8.92 ChEMBL
V2 V2R Rat Vasopressin and oxytocin A pKi 8.92 9.02 9.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database