CHEMBL3040325


SMILES COc1cccc(Nc2nc(Cc3ccccc3)nc3c2CCNCC3)c1
InChIKey BZDGCBXVIKXHFH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.3 6.3 6.3 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.52 7.52 7.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.04 8.04 8.04 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.43 7.43 7.43 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.03 6.03 6.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.11 7.11 7.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.07 7.07 7.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.08 6.08 6.08 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.79 6.79 6.79 ChEMBL