GPCRdb

CHEMBL321761

Agent/drug
Bioactivity

CHEMBL321761

SMILES	CC(C)N(C(=O)CN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1
InChIKey	ITMJPTIFWLPIOL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	7
Molecular weight (Da)	561.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCK₁	CCKAR	Human	Cholecystokinin	A	pKi	7.30	7.30	7.30	ChEMBL
CCK₂	GASR	Human	Cholecystokinin	A	pKi	7.60	7.60	7.60	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCK₁	CCKAR	Guinea pig	Cholecystokinin	A	pEC50	5.90	5.90	5.90	ChEMBL
CCK₁	CCKAR	Rat	Cholecystokinin	A	pIC50	6.60	6.60	6.60	ChEMBL
CCK₁	CCKAR	Human	Cholecystokinin	A	pIC50	7.26	7.29	7.30	ChEMBL
CCK₂	GASR	Human	Cholecystokinin	A	pIC50	7.60	7.61	7.62	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL321761

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.