CHEMBL3236553


SMILES Nc1nc(C2CCCC2)cc(N2CCNCC2)n1
InChIKey UYXWQSZIUMRFIW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 247.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pKi 7.7 7.7 7.7 ChEMBL
H4 HRH4 Mouse Histamine A pKd 8.0 8.0 8.0 ChEMBL
H4 HRH4 Human Histamine A pKd 9.5 9.5 9.5 ChEMBL
H4 HRH4 Human Histamine A pKi 8.92 8.96 9.0 ChEMBL
H3 HRH3 Human Histamine A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 8.14 8.14 8.14 ChEMBL