GPCRdb

CHEMBL322256

Agent/drug
Bioactivity

CHEMBL322256

SMILES	c1ccc(COC[C@@H]2CC[C@@H](c3c[nH]cn3)O2)cc1
InChIKey	RETVAMKTDRMQFH-ZFWWWQNUSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	258.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pKi	4.98	4.99	5.00	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	4.67	4.69	4.70	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	5.00	5.01	5.02	ChEMBL
H₄	HRH4	Human	Histamine	A	pEC50	4.89	4.89	4.90	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL322256

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.