GPCRdb

CHEMBL322275

Agent/drug
Bioactivity

CHEMBL322275

SMILES	COc1cccc2c1CCCC2CCCN1CCN(c2ccccc2)CC1
InChIKey	JGCUFOXBUYJGBX-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	6
Molecular weight (Da)	364.3

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.30	9.30	9.30	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Human	Adrenoceptors	A	pIC50	7.37	7.37	7.37	ChEMBL
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	9.30	9.34	9.44	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pIC50	6.96	6.97	7.01	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL322275

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.