GPCRdb

CYPRODIME

Agent/drug
Bioactivity

CYPRODIME

SMILES	COc1cccc2c1[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(OC)CCC(=O)C3
InChIKey	INUCRGMCKDQKNA-CEMLEFRQSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	4
Molecular weight (Da)	355.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Rat	Opioid	A	pKi	6.38	6.38	6.38	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	6.98	7.10	7.21	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	6.96	7.05	7.21	ChEMBL
μ	OPRM	Rat	Opioid	A	pKi	4.97	6.47	7.97	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	7.97	7.97	7.97	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	5.96	5.96	5.96	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	6.93	6.93	6.93	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	7.69	7.69	7.69	ChEMBL

Showing 1 to 3 of 3 entries

CYPRODIME

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.