CHEMBL3264743


SMILES CN1CC[C@@]23c4c5ccc(O)c4OCO[C@]46CC[C@@]2(O[C@H](C(=O)N4Cc2ccccc2)[C@H]63)[C@H]1C5
InChIKey GMYGREYAJXZCDV-VXDHFRBISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 7.63 7.63 7.63 ChEMBL
δ OPRD Mouse Opioid A pKi 8.71 8.71 8.71 ChEMBL
κ OPRK Guinea pig Opioid A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 6.85 7.4 7.96 ChEMBL
κ OPRK Human Opioid A pEC50 6.32 6.42 6.51 ChEMBL
μ OPRM Human Opioid A pEC50 5.87 6.41 6.95 ChEMBL