CHEMBL3104093


SMILES CN1CCc2c(c3cccc4c3n2CCc2ccccc2-4)C1
InChIKey XKGPHJMKJBEURD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 288.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.91 5.91 5.91 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.65 5.65 5.65 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.53 6.53 6.53 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.36 5.36 5.36 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.35 6.35 6.35 ChEMBL
H2 HRH2 Human Histamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.86 5.88 5.91 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.54 6.54 6.54 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.39 6.39 6.39 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database