GPCRdb

CHEMBL3264746

Agent/drug
Bioactivity

CHEMBL3264746

SMILES	O=C1[C@H]2O[C@@]34CC[C@@]5(OCOc6c(O)ccc7c6[C@@]3(CCN(CCc3ccccc3)[C@@H]4C7)[C@H]25)N1Cc1ccccc1
InChIKey	BOWOPEVIHUYMAZ-KRGIVBCISA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	550.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Mouse	Opioid	A	pKi	8.59	8.59	8.59	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	6.23	6.23	6.23	ChEMBL
μ	OPRM	Mouse	Opioid	A	pKi	7.34	7.34	7.34	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	7.69	7.87	8.04	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	4.90	4.90	4.90	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	6.19	7.42	8.64	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL3264746

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.