CHEMBL3289656


SMILES c1cnc(N2CCN(CCCc3nc4ccccc4s3)CC2)nc1
InChIKey PQVQCEDGSJVHMK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.41 8.41 8.41 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.55 6.55 6.55 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.59 6.59 6.59 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.07 6.07 6.07 ChEMBL
H1 HRH1 Human Histamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.39 7.39 7.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database