GPCRdb

CHEMBL3287396

Agent/drug
Bioactivity

CHEMBL3287396

SMILES	OCc1cc2cc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccn2n1
InChIKey	PIZUPLOSIUAOMH-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	448.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	7.80	7.80	7.80	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	6.62	6.62	6.62	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	8.51	8.57	8.64	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.89	8.89	8.89	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.46	7.46	7.46	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	6.27	6.27	6.27	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.23	8.23	8.23	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL3287396

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.