GPCRdb

CHEMBL3287403

Agent/drug
Bioactivity

CHEMBL3287403

SMILES	O/N=C/c1cnn2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc12
InChIKey	DWMNREQVNSYYID-WGOQTCKBSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	461.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	8.11	8.25	8.40	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	5.37	5.77	6.17	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	8.74	9.22	9.77	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.64	8.90	9.16	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	8.22	8.25	8.28	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pIC50	8.42	8.42	8.42	ChEMBL
D₂	DRD2	Human	Dopamine	A	pEC50	6.56	6.59	6.63	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	7.37	7.39	7.41	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL3287403

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.