GPCRdb

CHEMBL3290975

Agent/drug
Bioactivity

CHEMBL3290975

SMILES	OCc1cc(C(O)CNCCc2ccc(N3CCC(Cc4ccccc4)CC3)cc2)ccc1O
InChIKey	RJLSMWJFQOFTBK-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	4
Rotatable bonds	10
Molecular weight (Da)	460.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₁	ADRB1	Human	Adrenoceptors	A	pKi	4.10	4.10	4.10	ChEMBL
β₂	ADRB2	Human	Adrenoceptors	A	pKi	4.80	4.80	4.80	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₂	ADRB2	Human	Adrenoceptors	A	pEC50	6.30	6.30	6.30	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL3290975

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.