GPCRdb

CHEMBL1179

Agent/drug
Bioactivity

CHEMBL1179

SMILES	N[C@@H]1C[C@H]1c1ccccc1
InChIKey	AELCINSCMGFISI-DTWKUNHWSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	1
Molecular weight (Da)	133.1

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.22	5.22	5.22	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	8.28	8.28	8.28	Drug Central
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Rat	Dopamine	A	pKi	8.37	8.37	8.37	Drug Central
D₃	DRD3	Rat	Dopamine	A	pKi	8.31	8.31	8.31	Drug Central

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	4.75	4.75	4.75	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pEC50	5.82	6.02	6.21	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pIC50	5.68	5.68	5.68	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL1179

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.