GPCRdb

CHEMBL3322993

Agent/drug
Bioactivity

CHEMBL3322993

SMILES	COc1ccccc1N1CCN(CCCCNC(=O)c2cn3ccccc3n2)CC1
InChIKey	KDYAMWXNWWOJBI-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	407.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	7.72	7.72	7.72	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.46	8.46	8.46	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pIC50	7.58	7.88	8.18	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	8.52	8.84	9.15	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL3322993

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.