GPCRdb

CHEMBL1180343

Agent/drug
Bioactivity

CHEMBL1180343

SMILES	CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc(OC)cc2)C1
InChIKey	ZPASGLGRGIEHTG-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	7
Molecular weight (Da)	365.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	6.77	6.77	6.77	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pKi	5.96	5.96	5.96	ChEMBL
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pKi	5.86	5.86	5.86	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pKi	5.76	5.76	5.76	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pKi	6.38	6.38	6.38	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pIC50	5.71	5.71	5.72	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pIC50	4.42	4.42	4.42	ChEMBL
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pIC50	4.28	4.28	4.28	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pIC50	4.37	4.37	4.37	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pIC50	6.06	6.06	6.06	ChEMBL

Showing 1 to 5 of 5 entries

CHEMBL1180343

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.