CHEMBL3342859


SMILES COc1ccccc1N1CCN(CC2COC3(CCN(C(=O)c4ccccc4)CC3)O2)CC1
InChIKey LVRQFEKCQMNAQB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.17 7.17 7.17 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.97 7.97 7.97 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.69 7.69 7.69 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database