CHEMBL3342875


SMILES CCCCNC(=O)N1CCC2(CC1)OCC(CN1CCN(c3ccccc3OC)CC1)O2
InChIKey TXHNBTNTYPCQQT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 446.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.62 6.62 6.62 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.7 7.7 7.7 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.72 7.72 7.72 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database