CHEMBL319279


SMILES NC(CC1c2ccccc2Oc2ccccc21)(C(=O)O)[C@H]1[C@H](CCc2ccccc2)[C@@H]1C(=O)O
InChIKey BCMKQOREHHIJIN-KOUVAXTNSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 457.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 6.0 6.0 6.0 ChEMBL
mGlu7 GRM7 Human Metabotropic glutamate C pIC50 4.81 4.81 4.81 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pIC50 6.9 6.9 6.9 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pIC50 5.78 5.78 5.78 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pIC50 4.94 4.94 4.94 ChEMBL