GPCRdb

CHEMBL3344458

Agent/drug
Bioactivity

CHEMBL3344458

SMILES	CCCCc1cc2c(s1)C[C@H]1c3cc(O)c(OC)cc3CCN1C2
InChIKey	RJSAZDFVYLKJQV-KRWDZBQOSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	343.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.06	6.06	6.06	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	7.21	7.21	7.21	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.75	7.75	7.75	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.40	7.40	7.40	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	6.07	6.07	6.07	ChEMBL
D₁	DRD1	Human	Dopamine	A	pIC50	6.22	6.22	6.22	ChEMBL
D₂	DRD2	Human	Dopamine	A	pIC50	6.04	6.04	6.04	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL3344458

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.