CHEMBL320178


SMILES CCOC(=O)N1CCN(CCCOc2ccc(-c3ccc(C#N)cc3)cc2)CC1
InChIKey RFDSGHNJJQPTLS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 393.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.55 7.55 7.55 ChEMBL
H2 HRH2 Human Histamine A pKi 4.54 4.54 4.54 ChEMBL
H1 HRH1 Human Histamine A pKi 6.8 6.8 6.8 ChEMBL
H3 HRH3 Human Histamine A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database