GPCRdb

CHEMBL3354074

Agent/drug
Bioactivity

CHEMBL3354074

SMILES	O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCO)CC1
InChIKey	WOWRXMYCLGLRFQ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	11
Molecular weight (Da)	386.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	6.03	6.03	6.03	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	6.02	6.02	6.02	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.00	7.00	7.00	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pKi	6.45	6.45	6.45	ChEMBL
M₂	ACM2	Human	Acetylcholine (muscarinic)	A	pKi	6.68	6.68	6.68	ChEMBL
M₃	ACM3	Human	Acetylcholine (muscarinic)	A	pKi	6.20	6.20	6.20	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pKi	6.41	6.41	6.41	ChEMBL
M₅	ACM5	Human	Acetylcholine (muscarinic)	A	pKi	5.51	5.51	5.51	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pEC50	6.64	6.97	7.16	ChEMBL
M₁	ACM1	Human	Acetylcholine (muscarinic)	A	pIC50	5.94	5.94	5.94	ChEMBL
M₄	ACM4	Human	Acetylcholine (muscarinic)	A	pIC50	5.83	6.05	6.23	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL3354074

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.