CHEMBL3217984


SMILES CN1CCC2C(C1)c1cccc3c1N2c1ccccc1CS3
InChIKey YVENIGOVHPMTDH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 308.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.1 6.1 6.1 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.7 6.7 6.7 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.1 6.1 6.1 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.5 7.5 7.5 ChEMBL
H2 HRH2 Human Histamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
H1 HRH1 Human Histamine A pKi 8.5 8.5 8.5 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.3 6.3 6.3 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.2 7.2 7.2 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database