GPCRdb

CHEMBL3358509

Agent/drug
Bioactivity

CHEMBL3358509

SMILES	O=C(NCCCCN1CCN(c2ccccc2)CC1)c1ccc2ncccc2c1
InChIKey	OURPZJJZFFKVJH-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	388.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.00	7.00	7.00	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	7.18	7.18	7.18	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	9.22	9.22	9.22	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	6.96	6.96	6.96	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	5.75	5.75	5.75	ChEMBL
D₃	DRD3	Human	Dopamine	A	pIC50	6.59	6.59	6.59	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL3358509

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.