GPCRdb

conessine

Agent/drug
Bioactivity

conessine

SMILES	C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](N(C)C)CC[C@]5(C)[C@H]4CC[C@]23CN1C
InChIKey	GPLGAQQQNWMVMM-MYAJQUOBSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	0
Rotatable bonds	1
Molecular weight (Da)	356.3

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_2A	ADA2A	Human	Adrenoceptors	A	pKi	6.18	6.18	6.18	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	7.97	7.97	7.98	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	5.00	5.00	5.00	Guide to Pharmacology
H₂	HRH2	Human	Histamine	A	pKi	5.00	5.00	5.00	Guide to Pharmacology
H₃	HRH3	Human	Histamine	A	pKi	8.30	8.30	8.30	Guide to Pharmacology
H₃	HRH3	Rat	Histamine	A	pKi	7.18	7.59	7.91	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	8.27	8.31	8.46	ChEMBL
H₃	HRH3	Guinea pig	Histamine	A	pKd	6.55	6.55	6.55	ChEMBL
H₄	HRH4	Human	Histamine	A	pKi	5.00	5.00	5.00	Guide to Pharmacology

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.60	5.60	5.60	ChEMBL

Showing 1 to 1 of 1 entry

conessine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.