CHEMBL3393547


SMILES CN[C@@H]1CCN(c2ccnc(NC3CC4CCC3C4)n2)C1
InChIKey NZJVXVCSPDDULP-WCFLAILDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 287.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKd 10.1 10.1 10.1 ChEMBL
H4 HRH4 Human Histamine A pKi 9.1 9.1 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 5.5 5.5 5.5 ChEMBL