CHEMBL104574


SMILES COc1ccc2c(c1)CCN1Cc3c(ccc4[nH]c(C)c(C(=O)OCc5ccccc5)c34)OC21
InChIKey RNEMFGJTTJMEDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.95 5.95 5.95 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.14 7.14 7.14 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.87 5.87 5.87 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.93 5.93 5.93 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database