GPCRdb

CHEMBL338606

Agent/drug
Bioactivity

CHEMBL338606

SMILES	COc1ccccc1N1CCN(CCCCNC(=O)/C=C/c2ccc(F)cc2)CC1
InChIKey	ZIAICQQANCNQNU-JLHYYAGUSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	9
Molecular weight (Da)	411.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Pig	5-Hydroxytryptamine	A	pKi	6.48	6.48	6.48	ChEMBL
D₁	DRD1	Pig	Dopamine	A	pKi	5.96	5.96	5.96	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.57	7.64	7.68	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	9.16	9.32	9.47	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	7.37	7.37	7.37	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	8.77	8.77	8.77	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.41	8.41	8.41	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL338606

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.