CHEMBL104803


SMILES COc1ccc2c(c1)CCN1Cc3c(ccc4[nH]c(C)c(-c5nc(C)no5)c34)OC21
InChIKey LEYDLUKDXKBMCP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.21 5.21 5.21 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.51 5.51 5.51 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.66 5.66 5.66 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.12 5.12 5.12 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database