CHEMBL1182152


SMILES COc1cccc(OC)c1OCCNC[C@H]1COc2cc3ccccc3cc2O1
InChIKey DEXRYWBZRATHBC-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 395.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 6.74 6.74 6.74 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 5.61 5.61 5.61 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.05 6.05 6.05 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 5.46 5.46 5.46 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.47 7.47 7.47 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database