GPCRdb

CHEMBL339980

Agent/drug
Bioactivity

CHEMBL339980

SMILES	Cc1[nH]c2cccc(NC(=O)c3ccc(F)cc3)c2c1CCN(C)C
InChIKey	WMCLJWPYJWRZJT-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	5
Molecular weight (Da)	339.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.58	6.58	6.58	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	5.97	5.97	5.97	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	5.79	5.79	5.79	ChEMBL
5-HT_1F	5HT1F	Human	5-Hydroxytryptamine	A	pKi	8.09	8.09	8.09	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.00	6.00	6.00	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	6.17	6.17	6.17	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.66	5.66	5.66	ChEMBL
5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	6.42	6.42	6.42	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.75	5.75	5.75	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	5.84	5.84	5.84	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	4.42	4.42	4.42	ChEMBL
H₁	HRH1	Rat	Histamine	A	pKi	4.92	4.92	4.92	ChEMBL

Showing 1 to 12 of 12 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1F	5HT1F	Human	5-Hydroxytryptamine	A	pEC50	8.22	8.22	8.22	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL339980

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.