CHEMBL326263


SMILES N#Cc1ccc(CCOC(=O)N2CCN(CCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1
InChIKey JJKPSOUEWPDPFS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 503.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pIC50 5.47 5.47 5.47 ChEMBL
D5 DRD5 Human Dopamine A pIC50 6.0 6.0 6.0 ChEMBL
H2 HRH2 Human Histamine A pIC50 5.99 5.99 5.99 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.84 5.84 5.84 ChEMBL
H1 HRH1 Human Histamine A pIC50 6.1 6.1 6.1 ChEMBL
D4 DRD4 Human Dopamine A pIC50 6.11 6.11 6.11 ChEMBL
D1 DRD1 Human Dopamine A pIC50 5.95 5.95 5.95 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.64 5.64 5.64 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.71 6.71 6.71 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.15 6.15 6.15 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.99 5.99 5.99 ChEMBL
A3 AA3R Human Adenosine A pIC50 5.46 5.46 5.46 ChEMBL
μ OPRM Human Opioid A pIC50 5.83 5.83 5.83 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.65 5.65 5.65 ChEMBL