CHEMBL105261


SMILES CCC(=O)Nc1ccc2[nH]cc(C3CCN(C)CC3)c2n1
InChIKey ORJIHHLJBCQRBS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 286.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.26 8.26 8.26 ChEMBL
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.47 5.47 5.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pEC50 7.5 7.5 7.5 ChEMBL