GPCRdb

CHEMBL3421983

Agent/drug
Bioactivity

CHEMBL3421983

SMILES	O=C(c1ccc(F)cc1)N1CCn2c(nnc2-c2ccccn2)C1
InChIKey	DXQQRCJKVWAXDC-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	323.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NK₃	NK3R	Human	Tachykinin	A	pKi	5.30	5.32	5.35	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NK₃	NK3R	Human	Tachykinin	A	pIC50	5.40	5.45	5.50	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL3421983

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.