GPCRdb

CHEMBL344127

Agent/drug
Bioactivity

CHEMBL344127

SMILES	COc1ccc(CNC(=O)/C=C/c2ccc3[nH]cc(CCN(C)C)c3c2)cc1
InChIKey	LBVZWEWTNUDWNS-YRNVUSSQSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	8
Molecular weight (Da)	377.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	8.89	8.89	8.89	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	9.70	9.70	9.70	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	6.98	8.25	9.52	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NPS	NPSR1	Human	Neuropeptide S	A	Potency	6.80	6.80	6.80	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL344127

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.