CVN424


SMILES Fc1ccc(c(c1)F)OC1CCN(CC1)c1nc2CCN(Cc2nc1N[C@H]1COCC1)C(=O)C
InChIKey HSWVJQBEXRKOBZ-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 473.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR6 GPR6 Human A orphans A pKi 8.03 8.14 8.26 ChEMBL
GPR6 GPR6 Human A orphans A pKi 8.03 8.03 8.03 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR6 GPR6 Human A orphans A pEC50 4.42 5.81 7.2 ChEMBL