CHEMBL353087


SMILES COc1cc(NC(C)=O)c(Cl)cc1C(=O)NC[C@@H]1CCN(Cc2ccccc2)C1
InChIKey FUZBDAGWGHASHR-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 415.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.46 4.46 4.46 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 4.7 4.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database