GPCRdb

BREMAZOCINE

Agent/drug
Bioactivity

BREMAZOCINE

SMILES	CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc31)C2(C)C
InChIKey	ZDXGFIXMPOUDFF-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	315.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	8.64	8.88	9.05	PDSP Ki database
δ	A0A286XTF2	Guinea pig	Opioid	A	pKi	9.52	9.52	9.52	PDSP Ki database
κ	OPRK	Human	Opioid	A	pKi	10.40	10.40	10.40	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	10.10	10.31	10.52	PDSP Ki database
κ	OPRK	Guinea pig	Opioid	A	pKi	10.00	10.00	10.00	PDSP Ki database
μ	OPRM	Human	Opioid	A	pKi	8.85	9.19	9.70	PDSP Ki database

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pIC50	8.82	8.82	8.82	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pIC50	8.92	8.92	8.92	ChEMBL
μ	OPRM	Bovine	Opioid	A	pIC50	9.30	9.30	9.30	ChEMBL

Showing 1 to 3 of 3 entries

BREMAZOCINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.