GPCRdb

CHEMBL3577346

Agent/drug
Bioactivity

CHEMBL3577346

SMILES	CCCCn1cc(CCCOc2ccc(C(=O)NCCCCN(CCC)[C@H]3CCc4c(O)cccc4C3)cc2OC)nn1
InChIKey	OVKBSFKFSBQCLW-LJAQVGFWSA-N

Chemical Properties

Hydrogen bond acceptors	8
Hydrogen bond donors	2
Rotatable bonds	18
Molecular weight (Da)	591.4

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.15	6.15	6.15	ChEMBL
D₁	DRD1	Human	Dopamine	A	pKi	5.54	5.54	5.54	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	9.27	9.30	9.33	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	9.68	9.68	9.68	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	8.03	8.03	8.03	ChEMBL
D₅	DRD5	Human	Dopamine	A	pKi	6.16	6.16	6.16	ChEMBL

Showing 1 to 6 of 6 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	8.40	8.60	8.85	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL3577346

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.