CHEMBL3616847


SMILES N[C@@]1(C(=O)O)C[C@@H](Sc2nnc[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey YSOWRGMLMZQSBX-AVUIYAGVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.81 6.81 6.81 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.84 6.84 6.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu8 GRM8 Human Metabotropic glutamate C pEC50 5.0 5.0 5.0 ChEMBL
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 5.46 5.46 5.46 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 4.6 5.08 5.56 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 5.25 5.86 6.89 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.32 7.66 8.25 ChEMBL