CHEMBL1185857


SMILES COc1cccc(OC)c1OCCNC[C@@H]1COc2cc3ccccc3cc2O1
InChIKey DEXRYWBZRATHBC-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 395.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pKi 6.53 6.53 6.53 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.99 6.99 6.99 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database