GPCRdb

CHEMBL3616847

Agent/drug
Bioactivity

CHEMBL3616847

SMILES	N[C@@]1(C(=O)O)C[C@@H](Sc2nnc[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey	YSOWRGMLMZQSBX-AVUIYAGVSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	4
Rotatable bonds	4
Molecular weight (Da)	284.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Human	Metabotropic glutamate	C	pKi	6.84	6.84	6.84	ChEMBL
mGlu₃	GRM3	Human	Metabotropic glutamate	C	pKi	6.81	6.81	6.81	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₂	GRM2	Human	Metabotropic glutamate	C	pEC50	7.32	7.66	8.25	ChEMBL
mGlu₃	GRM3	Human	Metabotropic glutamate	C	pIC50	4.60	5.08	5.56	ChEMBL
mGlu₃	GRM3	Human	Metabotropic glutamate	C	pEC50	5.25	5.86	6.89	ChEMBL
mGlu₆	GRM6	Human	Metabotropic glutamate	C	pEC50	5.46	5.46	5.46	ChEMBL
mGlu₈	GRM8	Human	Metabotropic glutamate	C	pEC50	5.00	5.00	5.00	ChEMBL

Showing 1 to 5 of 5 entries

CHEMBL3616847

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.